Body Magnetic Resonance Research Group

Principal Investigator

Dimitrios Karampinos is a Group Leader in the Department of Diagnostic and Interventional Radiology in TUM, leading the BMRR Group since September 2012. He received his Diploma with honors from the Department of Mechanical Engineering in the National Technical University of Athens in 2003. In 2008, he received his Ph.D. from the Department of Mechanical Science and Engineering in the University of Illinois at Urbana-Champaign. Between 2009 and 2012, he was a Postdoctoral Research Scholar in the Musculoskeletal Quantitative Imaging Research Group of the Department of Radiology and Biomedical Imaging in the University of California, San Francisco. He completed his Habilitation in Medical Physics at TUM in March 2016. Dimitris is a TUM Junior Fellow, a Junior Fellow of the International Society of Magnetic Resonance in Medicine (ISMRM) and recipient of a European Research Council Research (ERC) Starting Grant.

Researchers

Christof Böhm joined the group as a physics student from the Technical University of Munich in February 2018. He is part of the master program “Applied and Engineering Physics” with an interest in biomedical topics. The program includes a one year full-time thesis project which focuses on water–fat imaging and body applications of quantitative susceptibility mapping.

Barbara Cervantes joined the group in November 2013 after obtaining a Master’s degree in Applied and Engineering Physics at TUM. In her previous studies at the University of Victoria, British Columbia, Canada, she focused in Astrophysics and Detector Electronics. In the BMRR group, she works on the development and application of acquisition methods and of quantitative diffusion methods for peripheral nerve imaging. Given the complexity of the acquisition techniques used in the group for peripheral nerve imaging, she also works on the development of simulation routines for such techniques.

  • I-An Chen , B.Sc
  • M.Sc. Student, Biomedical Computing

I-An Chen joined the group in February 2018 as a master student at Ludwig-Maximilian-University enrolled in the master program of “Material Science Exploring Large Scale Facilities”. During his bachelor studies, his research experience focused on experimental solid state physics. His master thesis project in the BMRR group concentrates on bone marrow magnetic resonance spectroscopy (MRS).

Michael Dieckmeyer joined the group in April 2014 being a medical student at TUM. He is enrolled in the doctoral program “Translational Medicine”, which is a structured graduation program for medical students of the TUM School of Medicine highly interested in research. The program includes one year of full-time research work followed by two more years of part-time research. Before starting medical school Michael graduated from TUM with a master’s degree in mathematics. His work is focusing on quantitative MRI and MRS methods in the context of bone marrow physiology and pathophysiology. Therefore, he is coordinating a study investigating the effects on certain parameters in female patients undergoing antiestrogen therapy.

Max Diefenbach joined the group in April 2015 after graduating from Ludwig-Maximilians-Universität München with a master’s degree in physics. During his education with a focus on theoretical physics, he studied in Lund/Sweden and Toulouse/France as an exchange and scholarship student. His projects in the BMRR group concentrate on water–fat imaging and body applications of quantitative susceptibility mapping.

Daniela Franz joined the group in summer 2015. She is currently doing her residency at the Department of Diagnostic and Interventional Radiology at TUM’s Klinikum rechts der Isar, after obtaining her medical degree at TUM in 2012. She earned her doctorate degree in August 2015. In summer 2016, she worked as a research fellow at the Department of Radiology at Memorial Sloan Kettering Cancer Center, New York, USA, for three months. During her residency she started working on MR imaging of brown adipose tissue. Her current work is focusing on metabolic imaging with an emphasis on adipose tissue imaging. Having a clinical background, she prepares and coordinates clinical studies.

Marco Hauke joined the group as a physics student at the Technical University of Munich in January 2018. In his master program he focusses on “Applied and Engineering Physics”. The program includes a one year full-time thesis project. In this project Marco Hauke investigates an alternativ way to compensate stimulated echoes for T2 mapping with multi-echo spin-echo sequences.

Sophia Kronthaler joined the group in April 2017 after graduating from Ludwig-Maximilians-University in Munich with a master’s degree in physics. While studying physics her focus was on theoretical physics in particular in statistical physics, nonlinear dynamics and complex systems. Her work in the BMRR group is focusing on the development of novel methods for quantitative susceptibility mapping of bone. Therefore her work includes ultra-short echo time imaging (UTE) techniques and multi-echo gradient-echo imaging.

Sean joined the group in February 2018 after obtaining a Master’s degree in Applied Mathematics and Physics from the Univerity of Glasgow, Scotland. His project within the BMRR group is on methodological body diffusion-weighted MRI, and involves the use of single-shot EPI to image the pancreas and liver, and 3D TSE to image the prostate.

Julio Oscanoa joined the group in February 2018 as a student of the TUM Master Program in Biomedical Computing. He studied electrical engineering at Universidad Peruana de Ciencias Aplicadas (UPC) at Lima, Peru with a focus in digital signal and image processing. With his profound knowledge in programming he is working on improving the group’s image reconstruction pipeline.

Stefan Ruschke joined the group in April 2013 after graduation in mechanical / medical engineering from the Technical University of Munich. His work is focusing on quantitative water–fat imaging and spectroscopy methods in bone and MSK applications. Recent projects include the development of precise and robust fat fraction quantification and the estimation of other related parameters such as T2 and T2’ using gradient echo imaging sequences.

Sarah Schlaeger joined the group in April 2016 being a medical student at TUM. She is enrolled in the doctoral program “Translational Medicine”, which is a structured graduation program for medical students of the TUM School of Medicine highly interested in research. The program includes one year of full-time research work followed by two more years of part-time research. In the BMRR group at the Department of Radiology, TUM, she works in the field of Magnetic Resonance Imaging in patients with neuromuscular diseases in collaboration with the Department of Diagnostic and Interventional Neuroradiology. Her aim is to improve currently used acquisition methods for muscle imaging by developing and comparing new sequences and to define quantitative MRI based biomarkers for fatty and edematous changes in affected muscles. Therefore, she is collecting data in patients with varied neuromuscular diseases and coordinating the course of a large-scale study.

Jan Syvaeri joined the group in April 2017 being a medical student at TUM. He is part of the doctoral program ‘Translationale Medicine’ of the TUM, which is a special graduation program of the TUM Graduate School, for medical students who have a special interest in medical research. The program includes one year of full-time research work followed by two more years of part-time research. In the BMRR group of the Department of Radiology, TUM, he works in the field of Metabolic Imaging in patients of different diseases. His main project has the aim to develop an early detection of cancer cachexia. Therefore, he is collecting data in patients with gastrointestinal cancer in a longitudinal study.

Mirjam Veen joined the group in April 2018. She is currently enrolled in the Biophysics master program at TUM. During her bachelor studies at the university of Heidelberg she took part in an exchange program with Leiden University /The Netherlands. She gained research experience at the DKFZ Heidelberg, with a focus on applications of quantitative susceptibility mapping. In the BMRR group she will continue investigating body applications of quantitative susceptibility mapping.

Dominik Weidlich first got in contact with the group in May 2014 for a short three month long summer internship. He studied physics at the TUM and had a strong focus on biophysics. After this first working experience in MRI he spent one semester abroad at the University of Edinburgh (Scotland) and came back to write his master thesis in the BMRR group. During his thesis, Dominik developed a sequence that enables fast, high resolution and reliable quantification of T2 in peripheral nerves and muscle. His work is now used in clinical studies to examine patients with neuromuscular diseases or lower back pain. After his master degree Dominik continued his work in the group and started his PhD in April 2016. For his doctoral project, he is looking into diffusion properties of adipose tissue in the human body. The main aim of this project is the investigation of the fat microstructure and the extraction of certain parameters that describe the properties of different types of fat. These parameters could be used to better characterize and ideally prevent metabolic diseases.

Mingming Wu obtained her Master’s degree in Electrical Engineering from Karlsruhe Institute of Technology in March 2014. She has collected experience in ZTE imaging and MR Thermometry before joining the group as a research associate in February 2018. Her work at BMRR focuses on the study of brown adipose tissue (BAT) in human adults. The differentiation from white adipose tissue and the quantitative characterisation of BAT using different MR contrast mechanisms are aimed at.

Christoph Zöllner joined the group in October 2017 after graduating from Ludwig-Maximilians-Universität München with a master’s degree in physics. His education focused on theoretical and medical physics, with a master thesis project on CT imaging in the context of proton radiotherapy. In the BMRR group of the Department of Radiology, TUM, he works on the development of techniques for water-fat imaging and MR spectroscopy of ectopic fat and adipose tissue depots.

Affiliates

Alumni

  • Fiedemann Freitag (Dr. med. student in Dr. med. thesis , Spring 2015 - Summer 2017)
  • Franziska Treibel (Physics BSc student in BSc thesis, Spirng 2016 and Physics MSc working student, Fall 2016 – Summer 2017)
  • Christian Cordes (Dr. med. student in Dr. med. thesis , Winter 2013 - Summer 2016)
  • Jun Shen (Computer Science M.Sc. student, co-supervised with Bjoern Menze, Winter 2014)
  • Paran Yap (MD student in summer internship, Summer 2014)
  • Florian Dold (Computer Science B.Sc. student in clinical project, Summer 2014)
  • Jun Shen (Computer Science M.Sc. student in praktikum, Winter 2013)
  • Laura Flores (Computer Science M.Sc. student in praktikum, Summer 2013)