Body Magnetic Resonance Research Group

Water–fat imaging and fat quantification

Research summary

Our technical work on water–fat imaging and fat quantification focuses on the following directions:

  • Development of SNR-efficient multi-echo gradient echo acquisition techniques for water–fat separation.
  • Robust fieldmap estimation in water–fat separation.
  • Removal of confounding effects in PDFF quantification using both imaging- and MRS-based techniques.
  • Development of MRS techniques to measure fat unsaturation.

Key publications

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  • Karampinos, D.C., Yu, H., Shimakawa, A., Link, T.M., Majumdar, S., Chemical Shift-Based Water/fat Separation in the Presence of Susceptibility-Induced Fat Resonance Shift. Magnetic Resonance in Medicine 68, 1495–1505.

  • Karampinos, D.C., Yu, H., Shimakawa, A., Link, T.M., Majumdar, S., T1-corrected Fat Quantification Using Chemical Shift-Based Water–fat Separation: Application To Skeletal Muscle. Magnetic Resonance in Medicine 66, 1312–1326.